The 11 Best Protein Powders for Muscle Gain of 2024

Protein is among the most widely used supplements for muscle gain, and for good reason. While it’s much easier to hit your daily requirements for carbs and fat, many athletes struggle to consume enough protein to build muscle. And with so many types of protein on the market, including whey, casein, and plant-based protein, finding the best protein powder for your needs and dietary preferences has never been simpler.

To ensure you’re finding the best protein powder for muscle gain, our team of experts tested more than 100 different products. We’ve considered various fitness goals and preferences to gather a diverse list, so there’s truly something for every athlete.

Best Protein Powders for Muscle Gain

• Best Protein Powder for Muscle Gain: Transparent Labs Grass-Fed Whey Protein
• Best Tasting Protein Powder for Muscle Gain: Jacked Factory Authentic ISO
• Best Protein Powder for Men’s Muscle Gain: XWERKS Grow
• Best Protein Powder for Women’s Muscle Gain: KOS Organic Plant Protein
• Best Mass Gainer Protein Powder for Muscle Gain: Transparent Labs Mass Gainer
• Best Digesting Protein Powder for Muscle Gain: ONNIT Grass-Fed Whey Isolate
• Best Natural Protein Powder for Muscle Gain: Legion Whey+
• Best Whey Protein Powder for Muscle Gain: Momentous Whey Protein Isolate
• Best Budget Protein Powder for Muscle Gain: Nutricost Whey Protein Powder
• Best Hydrolyzed Protein Powder for Muscle Gain: Dymatize ISO 100
• Best Casein Protein Powder for Muscle Gain: Optimum Nutrition Gold Standard 100% Casein

Video Review

After you’re done reading this article, check out our video review as BarBend’s Nick English breaks down our favorite protein powders for muscle gain in 2024.

https://www.youtube.com/watch?v=2s0bEkc5S_Q

How We Tested and Chose the Best Protein Powders for Muscle Gain

We gave more than 100 protein powders a try in our testing lab to get a well-rounded idea of all the products on the market. We wanted to find the highest quality products that could appeal to a broad variety of athletes, while helping them build muscle. Here are the factors we considered during testing:

Formula

Different products have different macro breakdowns and ingredient labels. In our search for the best protein powders for muscle gain, we prioritized products with high protein content and relatively low fat and carb totals.

We also favored products and brands that used as little artificial sugars, artificial flavors, or fillers as possible. We tried to include formulas that would work for different dietary restrictions, including plant-based protein. 

Our testers also considered added ingredients while narrowing the list. Some brands add digestive enzymes to their protein to help ease the discomfort some may experience with dairy.

Flavor

If you want to add a new protein powder to your supplement routine, you want to get a product that actually tastes good. We tried the most popular flavors of different protein powders, mixed with water in a shaker bottle, to get a good idea of the flavor quality.

Bag of protein powder opened and facing the camera in testing center.

Different people have different flavor preferences and recipes. So, we included brands that offer a variety of flavors that can appeal to just about any athlete. 

Solubility

Considering most folks prepare their protein with a shaker bottle, we did the same thing in our testing lab. Our testers took a look at which powders dissolved well and which left clumps and chunks after a thorough shake. We listed the smoothest, least gritty formulas we could find. 

Side Effects

Trying a new supplement involves some, well, trial and error. Some people may experience digestive discomfort after drinking a full glass of even the best whey protein powder, while others may get bloated with plant-based formulas. Our testers kept an eye on any unwanted side effects they experienced in the minutes and hours after sipping. 

Third-Party Testing

We value transparency in the products we choose and brands we prioritize. For that reason, our team puts a premium on options that have been third-party tested to help ensure readers they’re getting safe products with accurate labels.

BarBend has taken this a step further, working with an accredited third-party lab to test our favorite products for purity. We’ve recorded the results of each product we tested to give you a good look at different products on the market.

Best Protein Powder for Muscle Gain: Transparent Labs Grass-Fed Whey Protein

A good protein powder should prioritize high protein content to support your muscle growth goals, contain no fillers, and be easy to digest — Transparent Labs’ whey isolate protein powder checks all of these boxes.

Transparent Labs Grass-Fed Whey Protein Isolate prioritizes muscle gain with its 28 grams of whey isolate protein per serving. Considering this supplement contains only one to three grams of carbs and as little as one gram of fat per serving (130 to150 calories per serving depending on the flavor), our product tester gave the formulation a 5 out of 5. 

Transparent Labs Whey Protein Powder

Our team tried the seasonal Peppermint Hot Chocolate and absolutely loved the flavor. “The taste was exactly as described,” our tester, who is a certified personal trainer, said, giving the flavor a 5 out of 5. “All I needed was some marshmallows and it was just like a real hot chocolate.” While this flavor isn’t available right now (but keep your eyes peeled), we’ve also loved the milk chocolate. 

We also gave the overall solubility a 5 out of 5, considering we had zero issues with floaties or clumps — no one likes floaties when you’re trying to sip a protein shake. We mixed ours in a shaker bottle and it separated perfectly fine.

BarBend worked with an accredited lab to gather testing data on heavy metal content in Transparent Labs Whey Protein Isolate.

When it comes to price, Transparent Labs isn’t the cheapest, but it’s not crazy pricey, either. The $1.99 per serving ($59.99 for a container of 30 servings) is pretty standard. However, for those who are shopping on a budget, you can find options that are less than $1.50 per serving. So, we gave the product an overall 3.5 out of 5 for cost/value.

Best Tasting Protein Powder for Muscle Gain: Jacked Factory Authentic ISO

It can be difficult to consistently hit your allotted daily protein goal, but it doesn’t have to be flavorless. When it comes to delicious protein powder with 25 grams of protein per serving, Jacked Factory has you covered.

“I gave the fruity cereal flavor a try and it actually tasted like Fruit Loops,” our tester (a certified personal trainer) said, giving the taste an overall 4 out of 5. “It had a little bit of a medicinal aftertaste, though. Not enough to dissuade me from buying but may be good to know for some buyers.”

Jacked Factory Authentic ISO

Overall, our tester gave this protein’s formulation a 5 out of 5, thanks to its muscle-building focus. You get 25 grams of protein per serving (the exact macros may vary by a gram or two, depending on the flavor) with only one gram of carbs and half a gram of fat. 

We also liked that it mixed smoothly, earning a 5 out of 5 for solubility. Our testers had no issues mixing the powder and didn’t notice any clumps at the bottom of their shaker cup. However, “the fruity cereal powder is white but actually turns red when mixed,” our tester noted. This isn’t necessarily a bad thing, but it may stain if you spill it on a white countertop, which isn’t ideal.

BarBend worked with a third-party accredited lab to test Jacked Factory Authentic Protein. We looked at the product’s metal content, bisphenol content, and more.

Jacked Factory offers eleven flavors, including the standards like vanilla, chocolate, and unflavored. But you also get some unique options like Blueberry Muffin, Cinnamon French Toast, and Fruity Cereal Splash. Given the variety, there’s definitely something for everyone. 

We were also big fans of the price point, giving it an overall 4 out of 5 for price per serving. One 30-serving container costs $39.99, which is about $1.33 per serving. This is among the cheaper products, but for those on a tight budget, there are less expensive options.

While our testers didn’t notice any negative side effects after drinking a scoop, Jacked Factory does sweeten this powder with sucralose. Artificial sweeteners can cause digestive unrest for some, so it may not be the best pick for every athlete.

Best Protein Powder for Men’s Muscle Gain: XWERKS Grow

Protein powders aren’t really a gender-specific supplement. That being said, it can make a good fit for male athletes (or any athlete) looking to grow muscle. Grow’s formula consists only of New Zealand grass-fed whey protein, which has some of the strictest and highest standards for dairy quality. So, you won’t get any hormones, antibiotics, or pesticides in your whey protein. Plus, this one is third-party tested, so you can trust you’re getting what the label says.

We also thought Grow had a fantastic formulation, earning a 5 out of 5. One serving is only 110 calories (one of the lowest on this list), consisting of 25 grams of protein, only one to two grams of carbs, and zero to two grams of fat. So, if building strength is the priority and you don’t want to add many other macros to your daily diet, this is a solid pick.

XWERKS only uses natural flavorings and sweeteners, so the taste is hard to match. “The chocolate actually tastes like chocolate milk,” our tester, who is also a certified personal trainer, explained, giving the flavor a 5 out of 5. “This is probably the best protein powder I’ve ever sipped. It doesn’t taste artificial.”

Xwerks Grow Protein Powder

Plus, we had to give the product a 5 out of 5 for solubility, too. “I had no problems mixing this product,” our tester said. “This protein is so fine and smooth, you barely even need a blender ball.” Don’t expect to see any chunks or clumps with this protein.

XWERKS may sound too good to be true. Well, that’s not exactly the case, but unfortunately, high quality comes at a price. We had to give this whey a 3.5 out of 5 for price per serving, considering it’s nearly $2 per scoop. For some, the $59 price tag may be too much to pay each month. But if you can afford it, you won’t be disappointed. 

Best Protein Powder for Women’s Muscle Gain: KOS Organic Superfood Protein

There’s no one protein powder that’s ideal for a specific gender. That being said, one serving of KOS Organic Superfood Protein packs 30 percent of your daily iron needs. All adults need this nutrient but it’s especially crucial for those who menstruate, as iron is often lost during monthly periods.(12)

We also like that KOS Organic Superfood Protein is a totally plant-based vegan protein powder that packs 20 grams of protein per serving. But protein isn’t the only nutrient you’re getting. This formula provides up to 30 percent of your daily iron value, 40 percent of your daily B12, and 35 percent of your daily vitamin E. It also has a digestive enzyme blend to help prevent the discomfort and bloating some people may experience with protein powder.

However, one serving of KOS’ powder is 140 to 160 calories, including up to seven grams of fat and nine grams of carbs, which is more than most others on this list. On the plus side, though, you do get three grams of fiber (thanks to ingredients like chia seeds), which helps promote digestive regularity.

Tester scooping KOS Vegan Protein Powder

You do get plenty of flavor options, but some customers noted an artificial taste. “I landed on this protein powder when looking for a plant-based one without any artificial sweeteners,” one reviewer said. “Although the quality of the product is great and there are, in fact, no artificial sweeteners, this product is extremely sweet and the strong flavor of the monk fruit sweetener takes on a similar flavor to artificial sweeteners.”

Most reviewers didn’t seem to have any issues with the sweetness, though. You can also mix it with some other ingredients if you want to dilute some of the sweetness, as many customers love this as a smoothie addition. 

Best Mass Gainer Protein Powder for Muscle Gain: Transparent Labs Mass Gainer

In order to build muscle, you need to eat in a caloric surplus. But it can be tough to up your calories if you’re already eating plenty of solid foods. Transparent Labs’ Mass Gainer can help make this process a little easier. 

With 730 to 750 calories per serving (13 to 14 grams of fat, 106 to 110 grams of carbs, and 51 to 53 grams of protein), this mass gainer can help add some serious calories to your daily diet, earning an overall 4.5 out of 5 from our product testers. The macronutrients are balanced, giving your body what it needs to repair and build muscle mass.

Although you only get two flavor options (Sweet Vanilla and Chocolate Glaze Donut), we thought the taste was pretty accurate. Our product tester and certified personal trainer tried the chocolate flavor and said, “I thought it really tasted like a chocolate donut — the flavor was accurate.” But considering there was so little variety, we had to give the flavor an overall 4 out of 5.

Transparent Labs Mass Gainer in testing gym.

But for solubility, this mass gainer earned a 5 out of 5. “It dissolved smoothly with no clumping at the bottom of my shaker bottle,” our tester said. “The consistency was also smooth with no chalky or gritty taste.”

While the price per serving is a lot higher than the other supplements on the list, it’s actually pretty on par with other mass gainers on the market. One 15-serving container costs $79.99, making it about $5.33 per serving. This costs a pretty penny but considering how many calories you get per serving, think of it like paying for a small meal — however, considering it doesn’t have added vitamins and minerals, it shouldn’t actually serve as a meal replacement.

Transparent Labs created a mass gainer with gains in mind. With high macros across the board, this formula is here to support you in your quest for muscle growth.

Read our full Transparent Labs Mass Gainer Review.

Best Digesting Protein Powder for Muscle Gain: ONNIT Grass-Fed Whey Isolate

While most adults can pretty easily digest protein powder, that’s not the case for everyone. Luckily, ONNIT’s Grass-Fed Whey Isolate Protein includes digestive enzymes and probiotics to help ease stomach discomfort. “Onnit Whey Protein scores a 4.5 out of 5 for its formula, in my opinion,” according to Chelsea Rae Bourgeois, RDN. “The macro ratio is on point for its goals, and the enzyme blend is intriguing.” 

Our testers tried the Mexican Chocolate and were actually pretty impressed by the flavor. “I thought the flavor tasted pretty good,” one tester said, giving the taste a 3.75 out of 5. “I can actually tell the difference between this flavor and standard chocolate.” 

BarBend tester sampling ONNIT whey.

However, we weren’t huge fans of the texture. It was actually a little too thin for our preference. That being said, we gave the solubility a 5 out of 5. This powder dissolves really well and our product tester noticed zero clumps or floaties in their shaker cup. 

We didn’t notice any negative side effects while sipping this supplement, which is a huge plus (probably thanks to the digestive enzymes). However, we weren’t able to find any information on third-party testing for this product. We had to give ONNIT a 1 out of 5 in that category and wish the brand had some lab certifications.

While we like the ingredients in this formula, it isn’t the most cost-friendly protein powder. One 30-serving container costs $59.95, which is about $1.99 per serving. We had to give this product a 2 out of 5 for cost per serving, as you can definitely find some more cost-friendly options.

Best Natural Protein Powder for Muscle Gain: Legion Whey+

For athletes who want to prioritize all-natural ingredients in their supplements, Legion is the ideal brand. This protein uses only natural ingredients with no artificial sweeteners, flavors, food dyes, or fillers. Plus, the whey is made with milk from grass-fed and pasture-raised cows.

Overall, our testers loved this whey formulation, giving it a 5 out of 5. This supplement is relatively lean with only 100 to 130 calories per serving, including up to 23 grams of protein, zero to three grams of fat, and two to four grams of carbs. However, many of the other products on this list contain a little more protein (usually 25 to 28 grams), which may be a turnoff for some athletes.

A scoop of Legion Whey+ protein powder.

Legion delivers on flavor, too, earning a 4.5 out of 5 from our product tester, who also has his personal training certification. “The Cinnamon Cereal tastes just like a bowl of Cinnamon Toast Crunch,” our tester said. “However, I wish it were a little more pungent. The flavor is definitely accurate but I wish it were a tiny bit richer, like the cereal.” This whey also earned a 5 out of 5 for solubility, as our tester didn’t notice any clumps.

Unlike most other whey supplements, Legion’s whey is third-party tested. It’s certified to contain no banned substances by Labdoor, so what you read on the label is what you’re getting. 

BarBend worked with an accredited lab to gather testing data on the overall purity of Legion Whey+ protein powder.

However, all these benefits do come at a cost. We had to give this protein a 3.5 out of 5 for price per serving. At $1.99 per scoop, this is among the more expensive protein powders on the market. For many shoppers, paying $59.99 for a 30-serving container every month may be unrealistic.

Best Whey Protein Powder for Muscle Gain: Momentous Whey Protein Isolate

If you’re looking to gain muscle, whey protein is one of the best supplements to keep in your cabinet. Momentous Whey Protein Isolate is sourced from grass-fed cows and undergoes a micro-processing filtration, which may help sustain the protein’s amino acid profile. In short, Momentous makes a high-quality whey.

When it comes to formulation, our testers gave this product a 5 out of 5. With only 100 calories per serving, including three grams of carbs and 23 grams of protein, this is a pretty lean and simple formula. Plus, Momentous includes ProHydrolase, a digestive enzyme blend to prevent bloating and digestion difficulty. 

BarBend worked with an independent accredited lab to examine the purity and label accuracy of Momentous Whey Isolate protein.

After giving this protein a try, our tester, who is also a certified personal trainer, thought the formula was incredibly smooth and easy to sip, giving the taste a 4 out of 5. “The chocolate tastes a lot like hot chocolate without needing to mix it with milk,” our tester says. “I’d definitely buy this flavor again.” However, we do wish Momentous offered more flavors, as they only have Vanilla, Chocolate, and Unflavored. 

We also gave this supplement a 5 out of 5 for solubility. “I actually mixed a double dose (two scoops) with water and I didn’t notice any floaties or clumps,” our tester says. “The formula is very smooth and there’s no grittiness.”

There’s one pretty inevitable downside to this product: “It’s incredibly expensive,” our tester says. “The flavor is fantastic and it’s a high-quality product with third-party testing but the price tag is probably too much for most buyers.” Given the high cost ($2.70 per serving or $64.95 for 24 servings), we had to give Momentous whey a 1 out of 5 for price per serving. But if you can afford it, we think it’s a great, high-end option.

Best Budget Protein Powder for Muscle Gain: Nutricost Whey Protein Isolate

You don’t have to spend $70 a month on protein to get an effective, high-quality supplement. Nutricost Whey Protein Isolate is a high-quality protein with plenty of flavor options for only $1.52 per serving when you subscribe to recurring deliveries.

Nutricost has several size options, including a two-pound and five-pound container. The larger the size you buy, the more money you save but we decided to take a closer look at the five-pound option. This container costs $117.95 for 62 servings and when you subscribe, you only pay $94.36 for the container. Considering the manageable price point and delivery convenience, we gave the cost a 4 out of 5.

This has only 140 calories per serving, including a half a gram of fat, one gram of carbs and 30 grams of protein. We did have to give the formulation a 3.5 out of 5, though, because we wish the formula used natural sweeteners (Nutricost uses sucralose) and grass-fed whey, which you’ll find with most of our other picks.

You do get plenty of flavors, though, which is a bonus. Nutricost offers their protein in 10 different options, including some more unique flavors like Strawberry Acai and Cake Batter. After trying the Chocolate Peanut Butter, our tester gave the flavor a 5 out of 5. “I’m not the biggest peanut butter fan but this one was great,” they said. “It wasn’t too powerful and the peanut butter isn’t stronger than the chocolate.”

Even in just a shaker cup, this formula dissolves pretty well, according to our testers. We didn’t notice any big clumps or settling, so our team rated the solubility a 5 out of 5. Plus, the texture was pretty pleasing, especially when mixed with milk. 

Best Hydrolyzed Protein Powder for Muscle Gain: Dymatize ISO 100

Dymatize ISO 100 is a hydrolyzed protein powder, meaning that it is broken down from an isolate into a form that is even more rapidly digestible by the body. This form of protein is 95 percent protein by weight, which leaves a low carb, fat, and lactose content, making it a potentially better protein option for those looking to build muscle without adding many fats and carbs to their diet.

For the formulation, our testers (including certified personal trainers) gave Dymatize ISO 100 a 5 out of 5. One serving is only 120 calories, including half a gram of fat, two grams of carbs, and 25 grams of protein. We do want to note, however, that the specific macros vary slightly between flavors, so be sure to double check the ingredient label if you’re keeping close track of your daily intake.

Dymatize ISO 100 in testing garage.

While Dymatize does offer a variety of unique flavors, our tester gave the Cocoa Pebbles a 3.5 out of 5. “There’s nothing too special about the flavor. It’s definitely not the worst I’ve ever tasted but there are better-tasting options,” our tester said. “The Cocoa Pebbles flavor isn’t much tastier than other chocolate-flavored protein powders. I’d recommend mixing it with milk.”

After mixing in a shaker bottle, our tester didn’t notice any clumps, giving it a 4 out of 5 for solubility. “It mixes pretty thin, though, which I don’t love for chocolate protein,” they say. “I love drinking chocolate milk but this is more like chocolate water.”

This Gourmet Vanilla variety of Dymatize ISO 100 Hydrolyzed Whey earned an overall A grade for purity and label transparency from our independent accredited lab.

The price isn’t as high as some products on the market, but there are definitely cheaper options. We gave the price per serving a 3.25 out of 5, considering the $1.67 per serve price tag. One container is about $33.43 for 20 servings, which is less product than most other brands offer. However, you can subscribe to monthly deliveries for $31.76.

Our tester did give this product a 5 out of 5 for side effects, though. Hydrolyzed whey has very little lactose, which means you probably won’t experience any bloating or digestive trouble.

Read our full Dymatize ISO 100 Review.

Best Casein Protein Powder for Muscle Gain: Optimum Nutrition Gold Standard 100% Casein

Both whey and casein protein come from milk, but they’re absorbed differently. Your body absorbs and digests casein powders more slowly, meaning you get a slower release of amino acids compared to whey. That’s why casein is ideal to drink before bed for muscle recovery. It can still help promote muscle gain but won’t absorb as quickly as whey. Our best casein protein powder was this pick from Optimum Nutrition.

The overall formulation of this protein earned a 5 out of 5 from our tester. It only has 120 calories per serving with four grams of carbs, one gram of fat, and 24 grams of protein. This also contains 40 percent of your daily calcium value, which is more than most whey protein powders — also ideal if you don’t get enough calcium in your daily diet.

Our tester also gave the flavor a 5 out of 5 after trying both the Chocolate Peanut Butter and Chocolate Supreme. “I loved both of these flavors. They’re both smooth and rich,” they said. “I’d honestly say the chocolate supreme is practically as good as chocolate pudding.”

Unlike whey, which dissolves in liquid, casein gets pretty thick, according to our tester, who gave a 4.5 out of 5 for solubility. “I like to mix my casein into food or make protein pudding,” our tester said. “It mixes well but it doesn’t dissolve.” So, if you prefer to drink your protein in a shaker, you may want to opt for whey.

We do like that this product is third-party tested and Informed Sport-certified however, we had to give it a 2 out of 5 for price per serving. At about $2.15 per serving ($53.99 for a 25-serving container), it’s one of the pricier proteins on this list. Although casein is great for those who want a high-protein snack before bed, there are cheaper whey supplements that can help promote muscle gain, too.

[Related: The 6 Best Optimum Nutrition Flavors of 2024 (Taste-Tested)]

Benefits of Protein Powders for Muscle Gain

If you hit the gym consistently, you’ve likely seen someone drinking a protein supplement from a shaker bottle. Dietary supplements are an easy way to increase your protein intake to help support muscle gain. Read on to learn the many benefits of protein powder.

Note: Before you try any new supplements, be sure to talk to your doctor or a registered dietitian.

It May Help Promote Muscle Gain

There has been a wealth of research conducted on this topic, and it seems like protein powder may be money well spent, as protein supplementation may accelerate gains in not only muscle mass but aerobic capacity too. (1)

A scoop of Jacked Factory Authentic ISO.

When combined with resistance exercises like lifting weights, resistance bands, or even bodyweight exercise, protein supplementation may help kickstart muscle protein synthesis, which is the repair and rebuilding process for broken-down muscle fibers. (2) In theory, the faster you can repair those fibers and make them stronger, the more lean muscle you can build. (2) That’s why so many people opt to take a protein powder for muscle gain.

It’s Convenient

Getting protein from whole foods is always ideal but when you’re short on time, cooking chicken isn’t exactly convenient. Powder is easy to take on-the-go to increase your daily protein intake — all you need is some water and a shaker bottle. So, keeping a scoop of protein in your gym bag can be a quick way to increase your daily protein. 

It’s Versatile

There’s a seemingly endless list of foods you can make with some added protein powder. You can add a scoop to some pancake batter or mix it into your morning oatmeal or homemade ice cream. Protein powder makes it really easy to add protein to plenty of foods or desserts that generally aren’t a great source of protein.

[RELATED: Best Creatine Supplements]

How We Chose the Best Protein Powders for Muscle Gain

We considered a plethora of variables when putting this list together. We dove into supplement type, flavor, price, research, and dosage to make sure there is a pick that fits everyone’s needs when it comes to fueling muscle gains.

Protein Type

The type of protein in each supplement was an important factor for muscle goals. We looked at various forms, such as vegan proteins, whey isolates, whey concentrates, caseins, and hydrolyzed wheys. We also took into consideration the addition of other ingredients which may benefit recovery, micronutrients, and digestion. Our goal in including such a wide variety of protein types was to ensure there was a product that could suit every type of consumer. 

Flavor

If your protein tastes disgusting, you probably won’t want to sip it each day. So, we taste-tested more than 100 different proteins to find the most delicious products on the market. We know that taste is subjective, so we involved a variety of product testers to give a well-balanced review of each flavor.

Price

Protein powders vary in price depending on what type of protein is used, what the list of ingredients includes, and buying options, such as bulk buys. We wanted to pick a list that had options for a multitude of budgets, making protein powders accessible to anyone. For the most part, proteins can range anywhere from under a dollar to more than five dollars per serving. Our picks offer a wide range of prices, so there’s something for everyone.

Macronutrient Content

Macronutrient content is another big thing to consider when purchasing a protein powder supplement. Whether you’re cutting or bulking while trying to encourage muscle gains, your end goals will be the main driver behind this decision. We chose protein powders that varied in macronutrient content.

Our main focus was keeping protein content high and getting a mix of products with low fats and carbs, as well as some with higher fat and carb content. Since many of these picks are whey isolates, the fats and carbs tend to be a bit lower across the board. 

Micronutrient Content

Although macronutrients are the main drivers behind muscle gains, it is important to think about your micronutrients, as well. Micronutrients are the vitamins and minerals that your body needs in order to function properly. All of these picks have some micronutrients included, but it is always a good idea to know your own needs and supplement accordingly.

Mixing up Legion Whey+ protein powder.

If you’re eating a healthy, well-balanced diet, you probably won’t need extra micronutrients from your protein sources. We’ve included powders both with and without an extensive list of micros, so you can decide for yourself if you only want a few or if you’d rather knock all your nutritional needs out with one shake. 

[Related: How To Do The Romanian Deadlift For Lower-Body Size And Strength]

Dosage

Protein powders deliver different amounts of protein per serving based on their ingredients and processing. Hydrolyzed and isolate formulas contain a higher percentage of protein than other types, 95 and 90 percent protein by weight, respectively.

The picks on our list average between 20 and 30 grams of protein per serving, but if you look at the mass gainer, you’ll find over 50g of protein per serving. Rest assured that any product we have recommended contains a solid dose of protein, and doesn’t fall short compared to the rest of the market. 

How Much Do Protein Powders for Muscle Gain Cost?

Protein powders have a fairly narrow range of prices, especially when discussing high-quality protein powders — like we have on this list. Generally, protein powders feel expensive up front but end up being a reasonably cost-effective way of adding more protein to your diet when you’re trying to gain muscle. Protein powders are more expensive per gram of protein than traditional sources of lean protein, such as chicken, but you’re paying for the convenience and purity with a protein powder.

Best Protein Powder for Muscle Gain	Transparent Labs Grass-Fed Whey Protein	$59.99Per serving: $2.00
Best Tasting Protein Powder for Muscle Gain	Jacked Factory Authentic ISO	$39.99Per serving: $1.33
Best Protein Powder for Men’s Muscle Gain	XWERKS Grow	$59Per serving: $1.97
Best Protein Powder for Women’s Muscle Gain	KOS Organic Superfood Protein	$55.99Per serving: $1.99
Best Mass Gainer Protein for Muscle Gain	Transparent Labs Mass Gainer	$79.99Per serving: $5.33
Best Digesting Protein Powder for Muscle Gain	ONNIT Grass-Fed Whey Isolate	$59.95Per serving: $1.99
Best Natural Protein Powder for Muscle Gain	Legion Whey+	$59.99Per serving: $2.00
Best Whey Protein Powder for Muscle Gain	Momentous Whey Protein	$64.95Per serving: $2.70
Best Budget Protein Powder for Muscle Gain	Nutricost Whey Protein Isolate	$57.95Per serving: $1.90
Best Hydrolyzed Protein Powder for Muscle Gain	Dymatize ISO 100	$94.97Per serving: $1.36
Best Casein Protein Powder for Muscle Gain	Optimum Nutrition Gold Standard 100% Casein	$53.99Per serving: $2.15

Most protein powders for muscle gain cost somewhere between $45 and $65 for a container, while the price per serving is generally around $1.25 to $2.25. Notable outliers to these price ranges are mass gainers and very large containers of protein. Mass gainers are essentially large meals in powder form and can cost close to $100 for a container with a serving cost of $5.00 or more. 

[Related: 8 Best Protein Shakes of 2024 (Tested by Experts)]

What to Consider Before Buying Protein Powder for Muscle Gain

When you target muscle gains, there can be many factors to consider. Being realistic with your goals and considering dosage, type of protein, additional ingredients, and price are all things to think about when you’re purchasing any supplement.

Be Realistic

It’s important to be realistic when it comes to supplements for muscle gain or bodybuilding. Taking protein powder alone most likely won’t yield you the muscular results you’re looking for. The main way muscle is built is through resistance training, but proper nutrition and supplementation are also extremely important factors.

If you’re working out and not getting the proper amount of macronutrients, it can mean a loss of muscle mass. For example, carbs are the main source of energy in the body. If you don’t have proper glycogen stores, your body will use muscle in order to attain energy to utilize, and it will take a toll on muscle gains overall.(7)

Dosage

Depending on what your goals are, you want to consider dosages of protein in your powder, as well as other macros. You may want a protein powder that delivers a high protein content while keeping carbs and fats low if you’re cutting, just looking for a solid protein snack, or you prefer eating your carbs and fats rather than drinking them. If you’re bulking, you may want a higher macronutrient profile all around.

Type of Protein 

This list contains a wide variety of proteins, like whey concentrate, whey isolate, hydrolyzed whey, pumpkin seed protein, and pea protein. Depending on your lifestyle choices, dietary preferences, and needs, there may be one that is better suited for your goals than the others.

Scooping supplement into water.

Some people find that plant-based proteins are better on their stomach if they have issues digesting lactose, or if they choose a plant-based lifestyle. Hydrolyzed whey is another good option for those who have stomach issues, as the process to hydrolyze whey cuts the proteins into a more easily digestible form. Each type of protein will have pros and cons to them, so take some time to figure out what makes the most sense for you. 

Additional Ingredients

Your diet needs may be different during different phases of fitness or your life, and it’s important to factor in the additional ingredients listed in each formula. For example, if you’re looking to avoid artificial sweeteners, flavors, or ingredients there will be some powders on this list that won’t fit your needs.

If you want a protein that also contains BCAAs for recovery, you will want to opt for a formula that includes a solid dosage of them in their ingredient list. All the formulas in these proteins vary, so we suggest reading each label and ingredient list thoroughly before making a purchase. 

Price

Price can be an important factor when it comes to buying supplements. The formulas will vary by ingredients, quality, serving size, and formulation. This means that the price of each product will vary equally. If you’re opting for straight protein, and you don’t care much about the extra bells and whistles, you’ll potentially pay less per serving than you would for a formula that contains some extras, like BCAAs, or even one that has an all-natural formula.

Some types of protein tend to be more expensive than others due to the process they go through in manufacturing. For example, whey isolate tends to be more expensive than other forms, because its processing is a bit more extensive than other types of protein, making it leaner and potentially easier to digest. 

Types of Protein

There’s a wide variety of protein variations on the market, and each is unique for its formulation, macro and micronutrient content, flavor options, and origin source. You’ll find whey isolates, whey concentrates, pea and pumpkin seed protein, casein, and whey hydrolysate, to name some of the big hitters. Below, we dig into each type a little deeper.

Whey Protein

Whey protein refers to a group of proteins that are synthesized from cow’s milk. They contain the eight various proteins that are found in milk, including lactoferrin, lactoperoxidase, and immunoglobulins. (5)

These proteins are then treated to become various types of whey (concentrate, isolate, or hydrolyzed). Whey is a very common type of protein and is most often utilized because it is considered a complete protein — this means it contains all nine essential amino acids. An essential amino acid is an amino that is necessary for bodily functions but isn’t readily produced in the body and, therefore, must be consumed through food or supplement sources. 

Whey Isolate

Whey protein undergoes a pretty extensive refining process to become an isolate and therefore usually sports a higher price per serving. First, they separate the milk from the whey, then they pasteurize the liquid whey, and finally, the liquid whey is isolated. When it goes through this process, a lot of the carbs, fats, and lactose are taken out, leaving the formula at 90 percent protein content by weight.

Whey isolate is a form of whey protein that is low in lactose and, therefore, might be a better option for those with lactose intolerance.(3) It is always best to check with your healthcare professional before adding this to your supplement stack.

Whey Concentrate

A whey concentrate is usually between 30 and 89 percent protein by weight, and because it has to go through a less extensive process, it can be less expensive per serving.(3) This also means it generally has a bit higher carb and fat content than an isolate, although it may be relatively low still. Concentrate is also higher in lactose than an isolate, so it may be best to avoid it if you get digestive issues, or have an intolerance to lactose. 

Whey Hydrolysate

Hydrolyzed whey is the form of whey protein that contains the most protein by weight and is usually low in carbs and fats. Whey hydrolysate has been shown in studies to reduce exercise-induced muscle damage and may be beneficial for muscle gains due to better recovery time and high protein content. (8)

This type of protein is often used for nutrient deficiencies and is often in baby formula due to its shorter peptide chains, which make it more easily digested. (4) This form of protein may not be easy on the wallet, but some important aminos are lost through the hydrolysis process which cuts protein chains into smaller and more digestible parts. 

Vegan Protein

There are a multitude of vegan protein powders on the market including pea, soy, pumpkin, sunflower, and chia, to name a few. Many people opt for vegan protein powders as a lifestyle choice due to the ingredient list or to avoid certain allergens. Pea protein (one of the most common) is a type of protein that is high in BCAAs and can have similar effects to whey protein. (9)

The only piece that is missing when trying to make a complete protein is the amino acid methionine, which is found in other forms of plant-based proteins, like pumpkin seed protein. Pumpkin seeds are naturally rich in protein and fat and are high in the micronutrients zinc, magnesium, and iron. That’s why you will often find that vegan proteins are a blend of different types of plant proteins rather than just one.

Casein

Casein is a type of protein derived from cow’s milk. It may be more slowly absorbed than whey protein, keeping you fuller for longer. It may also be more beneficial when taken before bed, as it can be processed throughout the night.

Casein is full of peptides, which may result in better immune functions and have some benefits for digestion as well. (10)(11) Casein has also been shown to improve adaptations in muscle resistance training by an increase in muscle protein synthesis, mass, and strength. (6)

Final Word

As you work toward your gains, it’s important to properly supplement in addition to your resistance work for maximum results. Protein is the building block of muscle, and without proper nutrition/supplementation, you’ll have a much harder time reaching your goals.

This list is a guide to help you figure out which protein best suits your needs. We’ve taken into consideration the types of protein, macro and micronutrient content, price, servings, and customer goals when building this list. Whether you’re a beginner or a professional athlete, we’ve tried and recommended a protein for you here to help with muscle growth. Set your budget, figure out what type of protein powder you want and what macros/micros you need, then let this list guide you to hit your maximum gains. 

FAQs

References

1. Pasiakos SM, McLellan TM, Lieberman HR. The effects of protein supplements on muscle mass, strength, and aerobic and anaerobic power in healthy adults: a systematic review. Sports Med. 2015 Jan;45(1):111-31. doi: 10.1007/s40279-014-0242-2. PMID: 25169440.
2. Duarte NM, Cruz AL, Silva DC, Cruz GM. Intake of whey isolate supplement and muscle mass gains in young healthy adults when combined with resistance training: a blinded randomized clinical trial (pilot study). J Sports Med Phys Fitness. 2020 Jan;60(1):75-84. doi: 10.23736/S0022-4707.19.09741-X. Epub 2019 Sep 23. PMID: 31565912.
3. Pires AF, Marnotes NG, Rubio OD, Garcia AC, Pereira CD. Dairy By-Products: A Review on the Valorization of Whey and Second Cheese Whey. Foods. 2021;10(5):1067. Published 2021 May 12. doi:10.3390/foods10051067
4. Li J, Zhu F. Whey protein hydrolysates and infant formulas: Effects on physicochemical and biological properties. Compr Rev Food Sci Food Saf. 2024;23(3):e13337. doi:10.1111/1541-4337.13337
5. Ulluwishewa D, Mullaney J, Adam K, Claycomb R, Anderson RC. A bioactive bovine whey protein extract improves intestinal barrier function in vitro. JDS Commun. 2022;3(6):387-392. Published 2022 Sep 30. doi:10.3168/jdsc.2022-0245 
6. Dela Cruz J, Kahan D. Pre-Sleep Casein Supplementation, Metabolism, and Appetite: A Systematic Review. Nutrients. 2021;13(6):1872. Published 2021 May 30. doi:10.3390/nu13061872
7. Williams C, Rollo I. Carbohydrate Nutrition and Team Sport Performance. Sports Med. 2015 Nov;45 Suppl 1(Suppl 1):S13-22. doi: 10.1007/s40279-015-0399-3. PMID: 26553494; PMCID: PMC4672015.
8. Brown MA, Stevenson EJ, Howatson G. Whey protein hydrolysate supplementation accelerates recovery from exercise-induced muscle damage in females. Appl Physiol Nutr Metab. 2018 Apr;43(4):324-330. doi: 10.1139/apnm-2017-0412. Epub 2017 Nov 6. PMID: 29106812.
9. Babault N, Païzis C, Deley G, Guérin-Deremaux L, Saniez MH, Lefranc-Millot C, Allaert FA. Pea proteins oral supplementation promotes muscle thickness gains during resistance training: a double-blind, randomized, Placebo-controlled clinical trial vs. Whey protein. J Int Soc Sports Nutr. 2015 Jan 21;12(1):3. doi: 10.1186/s12970-014-0064-5. PMID: 25628520; PMCID: PMC4307635.
10. Li X, Lu X, Liu M, et al. The Immunomodulatory Effects of A2 β-Casein on Immunosuppressed Mice by Regulating Immune Responses and the Gut Microbiota. Nutrients. 2024;16(4):519. Published 2024 Feb 13. doi:10.3390/nu16040519.
11. Mohanty DP, Mohapatra S, Misra S, Sahu PS. Milk derived bioactive peptides and their impact on human health – A review. Saudi J Biol Sci. 2016 Sep;23(5):577-83. doi: 10.1016/j.sjbs.2015.06.005. Epub 2015 Jun 17. PMID: 27579006; PMCID: PMC4992109.
12. Mansour D, Hofmann A, Gemzell-Danielsson K. A Review of Clinical Guidelines on the Management of Iron Deficiency and Iron-Deficiency Anemia in Women with Heavy Menstrual Bleeding. Adv Ther. 2021;38(1):201-225. doi:10.1007/s12325-020-01564-y